Anticholinergic plants

Atropine-like reactions may occur with several plants, some of which are used by drug abusers. The major clinical manifestations are nausea, dry skin & mouth, tachycardia, mydriasis,delirium, hallucinations, convulsions and urinary retention (the anticholinergic toxidrome).

The most common plants are
  • Datura and Brugmansia species (aka Jimsonweed, Thornapple, Stinkweed, Jamestownweed, Devil's apple, Angel's trumpet, Loco seed, Melpitte, Green dragon, Stramonium and Apple of Peru.)
  • Atropa belladonna (Deadly nightshade)
  • Duboisia myoporoides (Corkwood)

Specific treatment consists of sedatives (diazepam), anticholinesterase inhibitors (physostigmine, tacrine), and avoidance of anticholinergic drugs (e.g. neuroleptics).

Other hallucinogens

  • Marijuana
  • Mushrooms (Psilocybe, Amanita)
  • Peyote
  • Morning Glory (Convolvulaceae) (LSD like)
  • Claviceps purpurea ( Ergot)
  • Nutmeg