PARACETAMOL HALF-LIFE CALCULATION

This patient has 2 concentrations taken 2 hours apart.
When plotted on the graph it is clear that the fall in paracetamol concentration is slower than the nomogram line. This suggests that the non-toxic conjugative pathways of metabolism are saturated and that hepatotoxicity is likely.
This technique is unlikely to have validity for short half-lives, when the samples are taken after 12 hours, or when the concentrations are low.
If the samples are collected too close together lab error and variation will make the interpretation more unreliable.

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YouTube

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Google Video

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TeacherTube

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Blip.TV

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YackPack

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Add your favorite media clips and applications to your wiki in three easy steps:

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