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=Salicylates=

===Objectives===
* Understand the mechanism and treatment of salicylate poisoning
* Understand effects of urinary alkalinisation

==Problem 1==

An 18-year-old girl, 60 kg, 5 hours previously ingested 80 x 300 mg soluble aspirin washed down with a large amount of cheap wine. She is nauseated, vomiting complains of buzzing in her ears. Drowsy but responds purposefully. Pulse 120, BP 105/60, RR 18
You order some investigations
* Breath Alcohol 0.16
* Glucose 6.4 mmol/L
* ABGs
** pH 7.32
** pCOB2B 28
** pOB2B 112
** HCOB3B 13
* Electrolytes Normal
* Urine pH 6

# Would you decontaminate her?
# Discuss her management, detailing your interventions and how you would monitor therapy.
# What is the implication of co-ingestion of alcohol (or other sedatives) in this situation?