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Monday, February 13

  1. page 2.1.1.4 Salicylates edited ... Potassium depletion occurs because of increased renal excretion and intracellular movement of …
    ...
    Potassium depletion occurs because of increased renal excretion and intracellular movement of potassium. Hypokalaemic patients are unable to produce an alkaline urine.
    Initially give the patient 1 mEq/Kg of sodium bicarbonate in 5% dextrose over one hour
    ...
    infusion of 0.25- 0.5 mEq/Kg
    ...
    5% dextrose
    Moderate

    Moderate
    to severe
    ...
    of blood pH. pH to correct systemic acidosis.
    If the urine pH does not rise to above 7.5 (paradoxical aciduria) in spite of correction of systemic acidosis and the production of a systemic alkalosis this usually indicates the patient is potassium depleted.
    Alkaline diuresis should not be attempted in patients who have evidence of pulmonary oedema or those with renal failure. These patients should undergo haemodialysis. Oral bicarbonate is contraindicated as it enhances salicylate absorption.
    (view changes)
    10:19 pm
  2. page 2.1.1.4 Salicylates edited ... Potassium concentration Potassium depletion occurs because of increased renal excretion and i…
    ...
    Potassium concentration
    Potassium depletion occurs because of increased renal excretion and intracellular movement of potassium. Hypokalaemic patients are unable to produce an alkaline urine.
    For mild toxicity addInitially give the patient 1 mEqmEq/Kg of sodium bicarbonate in 5% dextrose over one hour
    then start an infusion of 0.5 mEq/Kg
    per kg body weight to the first literhour of dextrose/saline. If alkalinisation is not achieved within several hours the dose may be repeated.
    Moderate
    sodium bicarbonate in 5% dextrose
    Moderate
    to severe
    ...
    blood pH. If
    If
    the urine
    Alkaline diuresis should not be attempted in patients who have evidence of pulmonary oedema or those with renal failure. These patients should undergo haemodialysis. Oral bicarbonate is contraindicated as it enhances salicylate absorption.
    Haemodialysis & haemoperfusion
    (view changes)
    7:36 pm

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